Podocyte regeneration

 There are a few potential therapies for podocyte regeneration, including ex-vivo or pharmacological interventions. [2] For example, studies have suggested that Notch, Wnt/ß-catenin, Wilms’ tumor-1, miR-193a and growth arrest-specific protein 1 may be involved in the regeneration process. [3] Additionally, some glomerular parietal epithelial cells (PECs) may act as progenitors of podocytes and may be activated in the human Bowman capsule after podocyte injury. [1] PECs and CoRL are potential candidates for podocyte progenitor cells after podocyte injury and may serve as a potential therapeutic target. [1] Therefore, PECs could be researched further as a potential method for podocyte regeneration therapy.